- Leading a Process Chemistry Section with approx. 15 co-workers (scientists and associates) according to the Roche Leadership Commitments.
- Supporting and delivering a portfolio of projects with focus on tides (oligonucleotides and peptides) by assigning resources, setting priorities and providing sound judgment for decision making and problem solving.
- Fostering the development of cost efficient and robust processes and process understanding by using state of the art science and methodologies to enable lean manufacturing.
- Providing scientific and technical input to projects teams and further develop your section towards a lean and agile organization.
- Supporting Roche's regulatory submissions by applying principles of Quality by Design to drug substance development and corresponding documentation while ensuring compliance with quality and regulatory requirements.
- Actively supporting the departmental digitalization and M&S efforts as well as contributing in defining the department's future technical and regulatory strategies and concepts
- A PhD degree in organic chemistry with at least 10 years' experience in process chemistry for synthetic molecules (including small molecule, oligonucleotides and peptides), spanning the entire range from route design, process development, process characterization and process transfer to commercial manufacturing. This is demonstrated by publications in scientific literature, patents and authoring of regulatory documents.
- Excellent people leadership skills and a strong ability to act visionary and be the catalyst, mentor and architect for teams and members. Profound experience as matrix leader of complex projects.
- Excellent knowledge in oligonucleotide and peptide chemistry and extensive experience in working with external collaboration partners in Europe, US and Asia
- Comprehensive understanding of sustainable process development and how to implement green chemistry concepts into manufacturing processes and excellent understanding of scientific methodology, principles of data integrity and good documentation practices
- Excellent communication skills and a strong ability of building and maintaining constructive and effective relationships with stakeholders as well as strong collaboration and team building skills
-
Spezialistin Verfahrenstechnik
vor 1 Woche
ELAN Personal AG Basel, SchweizRoche Schweiz schlägt die Brücke zwischen Pharmazie und Diagnostik. Wichtige Forschungs · - und Entwicklungsfunktionen sind hier angesiedelt. Für unsere langjährige Kundin, die F. Hoffmann-La Roche AG in Basel, suchen wir eine/n · **SpezialistIn Verfahrenstechnik (m/w/d) 100%**: ...
-
LifeMine Basel, SchweizHeadquartered in Cambridge, Massachusetts, USA, LifeMine is opening its European Headquarters in Basel. Our 4,000 m2 facility is in Klybeck, Basel, right next to the beautiful Rhine River and the train station, also close to City Center. The Klybeck area is home to many top US an ...
-
Administrative Assistant
vor 6 Tagen
CTC Resourcing Solutions Basel, Schweiz**_The Life Science Career Network_** · **Administrative Assistant** · Our client is a pioneer in Drug Discovery and Development and one of the frontrunners in Personalised Healthcare. As the world's largest R&D spender in the pharmaceutical and diagnostics domain, they work in a ...
-
Compound Manager
vor 1 Woche
Monte Rosa Therapeutics, Inc Basel, Schweiz FreiberuflerOverview: · **Responsibilities**: · - Assists the Compound Managers in organizing the compounds inventory · - Manually produces solutions from milligram amounts of neat compounds · - Measures volume of the prepared solutions · - Tracks various transfer steps through the use of a ...
-
Analytical Development
vor 2 Wochen
ALTOGEN AG Basel, SchweizALTOGEN is a Swiss engineering and consulting company specialized in life sciences with proven expertise in pharmaceuticals, biotechnology, medical devices. · With several years of experience, technical expertise and project coordination, we support our partners throughout all ar ...
-
ETH Zürich Basel, Schweiz**Postdoctoral position in Environmental Chemistry of Biodegradable Polymers**: · **100%, Zurich, fixed-term**: · The **Environmental Chemistry Group** in the Department of Environmental Systems Science (D-USYS) studies the fate of organic chemicals and macromolecules - both anth ...
-
Compound and Process Manager, Automation and
vor 1 Woche
Monte Rosa Therapeutics, Inc Basel, SchweizOverview: · Monte Rosa Therapeutics is seeking a highly skilled Expert in Automation and Compound Management in our Basel office. The position will implement automation projects for our sample management workflows and support basic compound management functions. · **Responsibilit ...
-
Associate Scientist
vor 3 Tagen
Coopers Group AG Basel, SchweizAssociate Scientist · We are looking for a person responsible for performing scientific experiments for the preparation and timely delivery of drug substances (DS) processes, procedures or data in collaboration with experienced team members. · **Responsibilities**: · - Plans, per ...
-
Regulatory Affairs Associate Cmc Manager
vor 2 Wochen
Source Group International Basel, SchweizPosted: · - Today- Location: · - Basel, Switzerland- Job Ref: · - BH Job Type: · - Contract- Salary: · - CHF40 - CHF44 per hour- Expiry date: · - 1/18/2023- Contact: · - Audwin Cheung- Xplore Life Sciences are recruiting for an Associate Regulatory Affairs CMC Manager to work for ...
-
Postdoc Oligonucleotide Synthesis
vor 1 Woche
Novartis Basel, Schweiz387446BR · **Postdoc Oligonucleotide Synthesis**: · Switzerland · **About the role** · We are looking for highly motivated Postdoc to support and further expand Novartis Oligonucleotide capacities in our Chemical and Analytical Development (CHAD) department Mixed Modality Unit. · ...
-
Pilot Plant Operator
vor 1 Woche
Solvias AG Basel, SchweizCompany information · Solvias is a world leading Swiss CRO/CMDO in contract research, development (Process R&D) and manufacturing (ISO, GMP). Our Products & Manufacturing Services Unit excels as a service provider in custom synthesis, catalysis and crystallisation development, as ...
-
CTC Resourcing Solutions Basel, Schweiz**The Life Science Career Network** · Our client, an innovative and dynamic bio-pharmaceutical company headquartered in Switzerland, covering multiple therapeutic areas, committed into delivering products on the market over the next 5 years, is looking a: · **Analytical Developme ...
-
Master Student for Icp ms of Oligos
vor 2 Wochen
Novartis Basel, Schweiz386758BR · **Master Student for ICP_MS of oligos**: · Switzerland · **About the role** · We are currently seeking a highly motivated and talented individual for an internship opportunity in the field of analytical method development for the characterization and quantification of ...
-
Research Associate/process Development
vor 5 Tagen
Coopers Group AG Basel, Schweiz**Research Associate/Process Development** · You will be involved in the execution of recombinant adeno associated viral vector (rAAV) production processes and execute experiments, develop production procedures and other relevant documentation. · **Responsibilities**: · - Culturi ...
-
Industry Sales Intern
vor 1 Woche
Arcondis Basel, SchweizABOUT ARCONDIS · Arcondis is a global consulting company with an exclusive focus on the healthcare and life science industries, with their particularly demanding requirements on quality and regulatory aspects. We have been managing challenges and solving problems for our clients ...
-
Associate Scientist
vor 13 Stunden
Hobson Prior Basel, Schweiz**Salary**: · Negotiable**Job type**: · Interim/Contract · **Location**: · Basel, Switzerland · **Function**: · Technical Operations, Discovery / R&D, Analytical · **Posted**:14/08/2023 · **Ref**: · BBBH23372 · - Hi I'm · Joshua · , I manage this role · Hobson Prior are currently ...
-
Process Engineering Section Manager
vor 1 Woche
OKJOB Basel, Schweiz_**Your main mission is to lead and organize a process engineering team in order to provide to the production reliable processes, tools and methods to achieve the company target.**_ · **Main responsabilities** · - Developing robust processes that ensure stable production · - Anal ...
-
Process Engineering Section Manager
vor 6 Tagen
OKJOB Basel, Schweiz_**Your main mission is to lead and organize a process engineering team in order to provide to the production reliable processes, tools and methods to achieve the company target.**_ · **Main responsabilities** · - Developing robust processes that ensure stable production · - Anal ...
-
Principal Scientist
vor 1 Woche
Novartis Basel, Schweiz6500 That's the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. · At Novartis, ...
-
Process Development Associate
vor 5 Tagen
CTC Resourcing Solutions Basel, Schweiz**The Life Science Career Network** · Our client is a pioneer in Drug Discovery and Development and one of the frontrunners in Personalised Healthcare. As the world's largest R&D spender in the pharmaceutical and diagnostics domain, they work in a vast number of drug discovery & ...
Section Head of Process Chemistry - Basel, Schweiz - Roche
Beschreibung
The Position
Due to internal progression, our Synthetic Molecules Technical Development department has an opportunity for a Section Head of Process Chemistry & Catalysis.
As the Section Head Process Chemistry, you will be working in the department "Process Chemistry & Catalysis" within the department "Synthetic Molecules Technical Development".
Synthetic Molecules Technical Development (PTDC) brings a broad range of experience across drug substance and drug product, and collaborates closely with key partners in Research and Early Development, commercial manufacturing and other technical functions. PTDC is responsible for technical development of our synthetic molecules pipeline (including oligonucleotides and peptides) and manufacture of drug substance and drug product for clinical studies across our synthetic molecules manufacturing network.
As section Head in Process Chemistry you lead a group of scientists and associates responsible for end-to-end process chemistry, from the design of new synthetic routes to the development of safe, robust and sustainable commercial manufacturing processes of synthetic drug substances (including oligonucleotides and peptides) throughout all clinical phases until transfer to commercial manufacturing. You will be reporting to the Head of Process Chemistry & Catalysis.
You will have the following responsibilities:
What you b ring: