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    Postdoc position in mesothelioma research 80-100%, Department of Thoracic Surgery - Zürich, Schweiz - Universitätsspital Zürich

    Universitätsspital Zürich background
    Beschreibung

    Your responsibilities

    The successful candidate will work on key parts of this collaborative project, funded by SNSF. The tasks include:
  • Selection of patient cohorts from the clinical database and preparation of samples including tissues, RNA, DNA. This may also include the preparation of single cell and bulk RNA sequencing libraries.
  • Collaborate and prepare samples for DNA methylation profiling by Illumina Infinium 450k array.
  • Establish in vivo mouse xenograft for PM (with bioluminescent and fluorescent imaging) using the already available 3D cell model, and perform treatment with new treatment agents
  • Perform analyses on the in vivo samples such as bulk or single cell RNA sequencing, cell culture, FACS, immunohistochemical/immunofluorescent stainings
  • Report the results and present at the monthly consortium meeting
  • In addition, the successful candidate will also take part in other ongoing projects for PM at our institution, that require similar technical approaches. Although, this project is limited to around 2 years, there is an option for extension.

    Your profile

    PhD in biology, biomedical science or a related science field. In addition to hands-on experience in cell culture and the standard biology methods, applicants must be willing to take a lead in performing experiments with mouse model. You have experience with tumor animal models, and LTK 1 already completed is a plus. You are willing to get familiarize with bioinformatics approaches or an experience with bioinformatics tools is a plus. You are fluent in English (writing and speaking) with high degree of flexibility and dedication to the project. Knowledge of German is a plus. You are able and want to work independently and enjoy challenges. You work accurately and in an organized manner. A good and accurate documentation of data and regular exchange with the direct supervisor is necessary. You have empathy and enjoy working in a team.


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