Phd / Doctoral Position - Zurich, Schweiz - Institute of Veterinary Anatomy, Vetsuisse Faculty of the University of Zurich

Beschreibung

Institute of Veterinary Anatomy, Vetsuisse Faculty of the University of Zurich_

PhD / Doctoral Position
The project is SNSF (Swiss National Science Foundation) funded.

The position is available for 3 years and will research into molecular mechanisms of hypoxia and HIF1α-mediated responses in steroidogenic cells (granulosa cells, Leydig cells and adrenal cells).

The employment will adhere to the salary rules of SNSF and UZH for doctoral students.

The focus of our research, STAR protein, plays a rate-limiting part in the provision of steroids and is an important factor in the regulation of homeostasis, affecting the role of several organ systems, including the reproductive organs and adrenals.

Thus, understanding the basic regulatory mechanisms involved in steroidogenesis is of special physiological and clinical relevance.

The multiple signaling events controlling steroidogenesis involve the cross-talk between different regulatory pathways, with hypoxia/HIF1a-mediated effects playing important roles as an integral part of physiological regulations.

The regulatory pathways described in our research group emphasize the need for further investigations into the complex nature of these processes (for more details see:
).

The acquired knowledge could potentially be applied for modulation of physiological

processes or for determining molecular mechanisms involved in the pathogenesis of steroid hormone-related clinical/pathological conditions.


Your responsibilities:

• Working on the research project, writing a dissertation
• Contribution to anatomical dissection courses for vetmed students is expected
• Previous experience in molecular and/or cell biology methods is welcomed but not mandatory
• Good command in English, willingness to learn German

What we offer:
We offer varied and interesting work in an inspiring and socially relevant environment.
- and cell-biology methods, dedicated international team and pleasant working environment in Zurich.


Place of work:
Veterinär-anatomisches Institut, Winterthurerstrasse, Zürich, Switzerland