Scientist for R&d Team in Cell Therapy - Grens, Schweiz - Cytiva

Cytiva

Geprüftes Unternehmen

Grens, Schweiz

vor 2 Wochen

Geschrieben von:

Lena Schneider

beBee Recruiter

Beschreibung

Be part of something altogether life-changing
Working at Cytiva means being at the forefront of providing new solutions to transform human health.

Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.

At Cytiva you will be able to continuously improve yourself and us - working on challenges that truly matter with people that care for each other, our customers, and their patients.

With associates across 40+ countries, Cytiva is a place where every day is a learning opportunity - so you can grow your career and expand your skills in the long term.

Forming part of the Biotechnology segment at Danaher, we bring together dedicated technical expertise and talent to develop the next generation of life-changing therapeutics.

Since 2017, 6 CAR-T cell therapies have been approved by FDA. These therapies allow for more than 40 to 60% complete response which is more than double alternative treatments. Nevertheless, there is still 20 to 30% failure to infuse a CAR T cell product to the patient.

Automatizing and standardizing CAR T manufacturing workflow will help mitigating many risks that could be responsible for these failures (i.e. contamination, manual handling, repeatability...).

However, scarcity of patient material forced technology development to utilize healthy donor materials during system design and verification testing, enabling design/performances challenges to be missed until late-development validation.

The development of a biological model able to mimic patient blood composition is thus essential to design and develop automated devices/system capable to provide performances realistic enough from a real case scenario.

In this role, you will have the opportunity to:

Join the R&D team and work closely with and interdisciplinary Cell & Gene Therapy product development team.
Deep understanding of diseases eligible for CAR T therapies
Deep understanding of autologous (manual and automated) CAR T manufacturing processes
Development of dynamic biological model capable to mimic blood cell composition of a maximum of disease eligible for a CAR T therapy
Participate to development/design of our devices by providing the biological model for testing and validate the model with patient material

The essential requirements of the job include:

M.Sc, PhD in cellular biology preferred
Experience in cell culture and flow cytometry is required
Strong analytical and problemsolving skills
Excellent communication and influencing skills and ability to gain buyin for ideas & initiatives
Strong desire to create clinical and commercial impact with your research
Demonstrated ability to work in a collaborative, crossfunctional and customerfocused environments

At Danaher, we value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve.

Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.